VSL#3 Probiotics for Digestive Health, IBS & UC Symptoms 60 Capsules

$65.95 $55.95

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VSL#3 capsules — Gold standard probiotic. 8 strains / 3 genera. Cold-stored & shipped. Dietary management for IBS, ulcerative colitis, and GI health. Trusted by professionals and patients.

  • Clinically supported: Backed by scientific research and trusted by healthcare professionals.
  • Ultra-high-potency, muti-strain blend: 112.5 billion CFU per capsule from 8 complementary probiotic strains to help maintain a balanced intestinal microbiota
  • Refrigerated to preserve potency: Stored and shipped cold to ensure live cultures stay potent throughout shelf life.
  • Precisely manufactured: Produced under GMP-certifed conditions, free from dairy, gluten, and other common irritants.
  • Typical adult dosage is 1-2 capsules up to 4 times daily, or as directed by a physician.
  • Swallow whole or mix into a non-carbonated cold beverage or food. Avoid consuming with hot foods or drinks, as heat may reduce probiotic
    viability.
  • Consistent use for several weeks may be needed to support microbiota balance.
  • For more information on how to take VSL#3 for the dietary management of certain GI conditions, please see the VSL#3 Product Information Sheet.
  • VSL#3 is a medical food intended to be used under medical supervision.
  • Probiotic strains: Streptococcus thermophilus, Bifidobacterium breve, Bifidobacterium lactis (previously classified as B. longum), Bifidobacterium lactis (previously classified as B. infantis), Lactobacilus acidophilus, Lactobacillus plantarum, Lactobacillus paracasei, Lactobacillus helveticus (previously classified as L. delbrueckii subsp. bulgaricus)
  • Other ingredients: Vegetal capsule hydroxypropyl methylcellulose), cornstarch, magnesium stearate, slicon dioxide, stearic acid, microcrystalline cellulose.

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$65.95 $55.95

Discover VSL#3 Capsules

The #1 gastroenterologist-recommended multi-strain probiotics brand

VSL#3 is a clinically studied, ultra-high-potency, multi-strain probiotic medical food. VSL#3 capsules are scientifically formulated for the dietary management of IBS and ulcerative colitis.

VSL#3 Benefits:

A Clinically Studied Medical Food
VSL#3 is a medical-grade formulation supported by clinical research.

Ultra-High Potency, Guaranteed
Contains 112.5 billion live bacteria (CFU) per capsule- an ultra-high-potency formula designed to keep its labeled potency through expiration when stored underrecommended conditions.

Multi-Strain
8 complementary strains from 3 different genera.

More Than a Probiotic. A Powerful Medical Food.

Pioneers in Probiotics. Leaders in Gut Health.

VSL#3 is an ultra-high-potency probiotic medical food - and the #1 gastroenterologist-recommended multi-strain probiotics brand. Developed for people with serious gastrointestinal conditions, it's trusted by healthcare professionals and customers alike for its scientific foundation, clinical credibility, and unwavering quality.

Built on Science. Proven in Practice.

Driven by research - not marketing trends -VSL#3 is trusted in clinical care for the dietary management of specific gastrointestinal conditions. It continues to set the standard for potency, consistency, and reliability in probiotic therapy.

Ultra-High-Potency. Guaranteed.

VSL#3 products deliver between 112.5 billion and 900 billion live bacteria per serving, depending on the formulation. Unlike many probiotics that only promise potency at the time of manufacture, VSL#3 guarantees potency through expiration when stored as directed.

Ultra-High-Potency. Guaranteed.

VSL#3 products deliver between 112.5 billion and 900 billion live bacteria per serving, depending on the formulation. Unlike many probiotics that only promise potency at the time of manufacture, VSL#3 guarantees potency through expiration when stored as directed.

Why Doctors Trust VSL#3

"The best product for IBD. I strongly recommend VSL#3”

Dr. Victor Gallo
Garden City Colon and Rectal Surgery Practice - Garden
City, NY

"I recommend VSL#3 for maintenance of a healthy gut microbiome."

Dr. George Barret MD
Founder and Chief of Gastroenterology Beth Israel Deaconess Hospital - Milton, MA

"I've had great success in using VSL#3 post colonoscopy, and especially so in my IBS and UC patients."

Dr. William Andy Shaver MD
Gastroenterologist - Lubbock, TX

VSL#3 Is Scientifically Formulated For The Dietary Management of IBS

Doctor Recommended
In a 2002 survey of gastroenterologists, 93% reported that IBS patients weresatisfied with VSL#3.

The most frequently observed benefits:

  • Less bloating
  • Reduced pain
  • Better stool consistency and frequency
  • Overall symptom improvement

Clinically Studied and FODMAP Friendly Certified forthe Dietary Management of IBS
In a 2021 clinical study, VSL#3R showed outcomes comparable to those achieved with a low FODMAP diet2 - a commonly recommended but restrictive approach. Because VSL#3 is certified FODMAP Friendly, it can also be used alongside a low FODMAP diet for flexible dietary management.

1. Data on file 2. Ankerson L, et al. J Med Internet Res. 2021; 23(12): e30291.

Clean Ingredients. Trusted Standards.

Dairy-Free

Gluten-Free

Soy-Free

Nut-Free

Vegan

No GMOs

It's What's on the Inside

Our unique 8-strain formulation is designed so each strain complements the others, helping maintain a balanced gut microbiota. Billions of live, beneficial bacteria work together to support digestive health.

Bifidobacterium

Bifidobacterium breve, Bifidobacterium lactis (previously classified as B. infantis), Bifidobacterium lactis (previously classified as B. longum)

Lactobacillus

Lactobacillus acidophilus, Lactobacillus helveticus (previously classified as L. delbrueckii subsp.bulgaricus), Lactobacillus paracasei,
Lactobacillus plantarum

Streptococcus

Streptococcus thermophilus

The #1 Gastroenterologist-Recommended Multi-StrainProbiotics Brand

Trusted by healthcare professionals and millions of customers worldwide, VSL#3 is a gold standard in multi-strain probiotics - recommended by experts for quality, consistency, and proven performance.

VSL#3 combines 8

complementary probiotic strains from 3 different genera to support gut microbiota diversity and digestive balance

VSL#3 is distributed in over 40

countries and counting-it's trusted by healthcare protessionals and patients worldwide.

VSL#3 is Dairy-Free

for individuals who avoid dairy due to dietary preferences or sensitivities.

VSL#3 Capsules: Clean Ingredients. Verified Quality.

Free From Common Irritants:

  • Dairy-Free
  • Gluten-Free
  • Soy-Free
  • Nut-Free
  • No GMOs
  • Vegan

Certified for Peace of Mind:

  • FODMAP Friendly Certified
  • Halal Certified
  • Kosher Certified

FAQs

VSL#3 is an ultra-high-potency probiotic medical food intended for the dietary management of irritable bowel syndrome (IBS), ulcerative colitis (UC), and an ileal pouch (pouchitis).

VSL#3 should be stored under refrigeration at 36-46°F (2-8°C) to preserve potency. It can remain at room temperature for up to 2 weeks without reducing effectiveness.

Medical foods are formulated for the dietary management of diseases or conditions with distinctive nutritional needs that cannot be met by diet alone. Unlike dietary supplements, medical foods are intended for use under a healthcare provider's supervision.

In a 2021 clinical study, VSL#3 demonstrated dietary management outcomes in people with IBS comparable to those achieved with a low FODMAP diet1 - a commonly recommended but restrictive approach. Because VSL#3 is certified FODMAP Friendly, it can also be used alongside a low FODMAP diet for flexible dietary management.

1Ankerson L, et al. J Med Internet Res. 2021; 23(12): e30291.